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filingDate 2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a918ce2671083695525663399ded2bb
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publicationDate 2012-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20120021249-A
titleOfInvention Preparation method of iron oxide nanocapsules, iron oxide nanocapsules and MRI contrast agents using the same
abstract The present invention relates to an iron oxide nanocapsule for MRI contrast agent with excellent contrast and a method for producing the same. Iron oxide nanocapsules encapsulated in a capsule material comprising, there is a characteristic that satisfies the following relations 1, 2, 3, 4 and 5. (Relationship 1) 5 ≤ 100 * D m (IO) / C v (IO) (Relationship 2) 2.5 ≤ 100 * D m (Cap) / C v (Cap) (Relationship 3) 0.5 wt% ≤ F (IO) ≤ 50 wt% (Relationship 4) 1nm ≤ D m (IO) ≤ 25nm (Relationship 5) 50nm ≤ D m (Cap) ≤ 200nm (D m (IO) in the relation 1 is the average size of the iron oxide nanoparticles, C v (IO) is the standard deviation in the size distribution of the iron oxide nanoparticles, in the equation 2 D m (Cap) is iron oxide nanocapsules Is the average size of, C v (Cap) is the standard deviation in the size distribution of the iron oxide nanocapsules, F (IO) in the equation 3 is the weight percent of the iron oxide nanoparticles encapsulated in the iron oxide nanocapsules, D in the equation 4 m (IO) is the same as the definition of relation 1, D m (Cap) in the relation 5 is the same as the definition of relation 2.
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type http://data.epo.org/linked-data/def/patent/Publication

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