| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_161ed56cc05f4ccdc84fdd0ee0971474 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| filingDate |
2003-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f8131f03a1428f37940fe43f35123bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66db211a0f9043e71ae8bf1ab531606c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737d3b1e7c1d04bd0db25cced865f277 |
| publicationDate |
2003-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20030069115-A |
| titleOfInvention |
Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues |
| abstract |
The present invention relates to a method for isolating cultures of cord blood-derived mesenchymal stem cells and progenitor cells and to induce differentiation into mesenchymal tissue.n n n In the cell isolation culture method of the present invention, the cord blood is superimposed on Ficoll-Hippack solution, followed by centrifugation to obtain mononuclear cell layer precipitation, and the cells obtained by monolayer culture of the mononuclear cells are treated with antibodies against mesenchymal stem cell / progenitor cell specific antigens. After reacting for a certain time, only the cells bound to the antibody are separated and cultured using a cell separator to obtain mesenchymal stem cells and progenitor cells having high purity and excellent viability.n n n The mesenchymal stem cells and progenitor cells of the present invention have the ability to differentiate into various mesenchymal tissues such as chondrocytes or bone cells under appropriate differentiation medium and conditions.n n n Therefore, the mesenchymal stem cells and progenitor cells can be mass-produced through the cell isolation culture method of the present invention, and the resulting cells can be usefully used for the regeneration and treatment of damaged mesenchymal tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8506948-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8614191-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9580687-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7816137-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332715-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014035215-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010056075-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100812544-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10238692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294456-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9439931-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005073366-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007011088-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007024036-A1 |
| priorityDate |
2002-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |