http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030025132-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03032f57426ed9ab4b609a3f8ece5d28 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate | 2001-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efadbef0446b8f04901f51eb762397ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45c2e18e755b234088d4318ac04f5153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34e35cb59344b46c8931b6271782f5bb |
| publicationDate | 2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030025132-A |
| titleOfInvention | A process for screening potential endocrine disrupting chemicals using a yeast two-hybrid system and transformed yeast strains therefor |
| abstract | The present invention includes a first expression vector containing a gene of the first protein in which a DNA binding domain and a sex hormone receptor or a ligand binding domain of a sex hormone receptor are fused, a coactivator of the sex hormone receptor, and a transcriptional activation domain are fused to each other. Endocrine transgenic yeast strains comprising a second expression vector expressing a gene of a second protein and a third expression vector expressing a reporter gene linked to be expressed under the DNA site to which the DNA binding domain binds and expressing these genes Incubating with a substance that is expected to be a disturbance, and analyzing the transcriptional activity of the reporter gene to determine whether the substance that is expected to be an endocrine disruptor is an antagonist or an agonist for the hormone receptor. A method for selecting endocrine disruptors and a yeast strain used therein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100476342-B1 |
| priorityDate | 2001-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 365.