http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100476342-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-201 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2005-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100476342-B1 |
| titleOfInvention | Method for detecting endocrine disruptors using yeast two-hybrid system containing hERα gene and co-activator gene |
| abstract | The present invention relates to a method for detecting chemicals having endocrine disrupting activity in humans using yeast, and more particularly, to activate transcription of a target gene depending on a ligand. The present invention relates to a method for detecting endogenous disorders (estrogenic chemicals) using the characteristics of the receptor hormone in the nucleus, which introduces a human-derived estrogen receptor α and a transcriptional co-activator into yeast. A method of detecting estrogen-like substances with endocrine disorders by expressing a two-hybrid system, monitoring the expression of reporter genes introduced on the chromosome and measuring ligand dependent transcriptional activation of the estrogen receptor It is about. According to the method of the present invention, it is possible to detect a specific chemical that affects the endocrine system of a human or an animal with a simpler and faster biological method for a large number of chemicals in the environment without using mammals or fish. . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190120683-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591632-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100748182-B1 |
| priorityDate | 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.