abstract |
The present invention relates to an inhibitor of apoptosis and an agent for preventing and treating diseases associated with apoptotic death using carnosine of Formula 1 as an active ingredient. Specifically, the present invention reveals that carnosine effectively inhibits cell-mediated cell death mediated by mitochondria, and thus cannosine, known only as an antioxidant or aging inhibitor, to Alzheimer's disease, stroke, epilepsy, Parkin's disease, myotonic dystrophy, Degenerative cranial nerve diseases such as Fraxil's disease and Huntington's disease; Immune system diseases such as AIDS; It provides a new use as a prophylactic and therapeutic agent for diseases related to cell death, such as diabetes or rheumatoid arthritis. |