http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20010040677-A
Outgoing Links
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-2875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-7062 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-46 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 |
filingDate | 1999-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20010040677-A |
titleOfInvention | Osteoimplant and method for its manufacture |
abstract | The present invention provides a bone implant, which has excellent mechanical strength and biocompatibility by chemical bonds formed between adjacent surface-exposed collagen of partially deionized bone material from which the bone implant is made, and through certain embodiments, bone treatment Activity and the ability to include bone growth agents can both accelerate and accelerate bone growth.n n n It is therefore an object of the present invention to provide a bone graft with good mechanical strength and biocompatibility, consisting of one solid aggregate of bone inducers bound to each other through chemical bonding between surface exposed collagen between adjacent bone inducers.n n n It is a further object of the present invention to provide a bone graft which may optionally include other ingredients such as reinforcing particles or fibers, fillers, medical and surgical bone growth inducers, mixtures thereof.n n n Another object of the present invention is to provide pores, perforations, apertures and channels to allow for more efficient penetration of endogenous and exogenous bone therapeutics and blood supply. To provide a bone graft with a network of spaces and spaces, and to provide a means to combine one or more bone therapeutics at the same time.n n n It is also an object of the present invention to provide a bone graft that can have a variety of shapes and sizes without mandatory limitation by the size or shape of the donor bone suitable for the configuration of the bone graft.n n n Another object of the present invention is to provide a method for producing a strong and biocompatible bone graft having any size and shape for transplantation.n n n In order to achieve the above object and another object of the present invention, there was provided a bone graft composed of one solid aggregate of bone inducers bound to each other through chemical bonding between surface exposed collagen between adjacent bone inducers.n n n In addition, providing a plurality of bone inducers exhibiting surface exposed collagen to achieve the object of the present invention, and forming a chemical bond between the surface and the exposed collagen to bind the bone inducer into one solid aggregate It provided a method for producing a bone graft comprising a.n n n The bone graft according to the present invention has the advantage of having excellent biocompatibility, non antigenicity, and mechanical strength compared to the prior art.n n n Another advantage of the present invention over conventional bone grafts is the ability to transport and efficiently diffuse one or more bone growth inducers to promote new bone growth and treatment.n n n The term "osteogenic" as used hereinafter refers to the ability of a substance to cause the production of new bone, whereby living cells are involved with the interior of the substance to induce bone formation.n n n The term "osteoconductive" as used below refers to the ability of a substance or material to provide biological inert surfaces to accept the growth of a new host bone.n n n The term "osteoinductive" as used below refers to the ability of a substance to replenish cells from a host having the ability to repair bone tissue.n n n The term "bone-derived elements" can be of any size and of any thickness and can be obtained by milling, slicing, cutting, or machining a bone. Refers to a piece of bone that can have any appearance, such as capable particles, fibers, stripes, thin to thick sheets.n n n The term " surface-exposed collagen " refers to the result obtained by deionizing the bone inducer, which is essentially when the bone inducer is the primary collagen. Substantially complete, to the extent that only the surface of the bone inducer provides exposed collagen, can be performed either partially or only superficial. Partial or surface deionization produces bone inducing substances with surface binding regions that are exposed collagen that maintain enhanced regions, which are non-affected ionized regions of bone inducing substances. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200104129-A |
priorityDate | 1998-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.