| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_942782ef91e65ecc67141721d44d38eb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
| filingDate |
2019-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef91413d3cecc75ea8e538eec6d1e27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99cfe327659e4c0745ead12000cf9db0 |
| publicationDate |
2019-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-102054104-B1 |
| titleOfInvention |
A New salt form of Tenofovir alafenamide, Method for Preparing or Use Thereof |
| abstract |
The present inventors have conducted research to develop a novel salt form that can enhance the pharmacological effect by overcoming the problems of low water solubility and oral absorption rate of only 1% of tenofovir alafenamide hemifumarate currently on the market. Tenofovir alafenamide heminafasylate, which has a water solubility of 240 times higher than that of nopovir alafenamide hemifumaric acid, can be used as a therapeutic or prophylactic pharmaceutical composition for the treatment of HIV-1 infection and chronic hepatitis B. . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220141457-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023282698-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020222393-A1 |
| priorityDate |
2019-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |