abstract |
The present invention provides a novel method of reducing the serine protease and / or serine protease zymogen content of plasma derived protein compositions. Also provided is a method for producing a plasma-derived protein composition with reduced serine protease and / or serine protease zymogen content. In another aspect, the invention provides aqueous and lyophilized compositions of plasma-derived proteins with reduced serine protease and / or serine protease zymogen content. Another embodiment includes a method of treating, managing and / or preventing a disease, including administration of a plasma-derived protein composition with reduced serine protease and / or serine protease zymogen content. |