http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101567921-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101567921-B1 |
| titleOfInvention | The composition for preventing and treating retinal degenerative diseases containing Otx2 protein |
| abstract | The present invention relates to a composition for preventing and treating abnormalities of mitochondrial diseases comprising OTX2 protein as an active ingredient. Specifically, the single defect of Otx2 gene reduces visual function and electroretinogram (ERG) Cone photoreceptors and bipolar cells, and in particular to severe degeneration of type-II OFF-conical bipolar cells, and also to Otx2 heterozygous mutant mouse-injected Otx2 Confirming that the protein significantly regulates the activity of mitochondria through the retinal nerve cells, it was confirmed that the composition containing the OTX2 protein of the present invention as an active ingredient can be effectively used for prevention and treatment of abnormal mitochondrial diseases . |
| priorityDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 547.