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filingDate 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_112558250fd5311379568744e339f2ac
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publicationDate 2013-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101334011-B1
titleOfInvention Anastrozole-Containing Sustained-Release Polymer Microspheres
abstract The present invention relates to an anastrozole-containing sustained-release polymer microspheres, and more particularly, to a method for producing polymer microparticles in which a polymer compound and anastrozole are dissolved in a solvent and aggregated into fine particles; The average serum of anastrozole for the treatment of the agglomerated polymer fine particles in an alcohol aqueous solution discharge period concentration (C ave) maximum serum concentration (C max) ratio of 1 to 20 ANA manufacturing straw sol containing-release polymer microspheres for The present invention relates to a polymeric microsphere prepared by the method and a pharmaceutical composition comprising the same. The method for producing an anastrozole-containing sustained-release polymer microparticles according to the present invention can produce polymer microparticles which lower the ratio of the maximum serum concentration (Cmax) to the average serum concentration (Cave) of anastrozole during the release period to 1 to 20. Since it is possible to use, it is effective to prepare a pharmaceutical composition for treating sustained release cancer having sustained release using the same.
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