http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101149821-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4412 |
| filingDate | 2010-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2012-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101149821-B1 |
| titleOfInvention | New Preparation Method of Diphenyl Acetate Derivatives |
| abstract | The present invention provides a safe and efficient method for preparing propiberine hydrochloride of formula (I), which is an agent for the prevention and treatment of urinary incontinence and urinary incontinence caused by irritable bladder diseases such as neurological bladder disease, neuroanguria disease, unstable bladder disease, chronic cystitis and chronic prostatitis. In more detail, 2-halo-2, 2-diphenylacetate derivatives are prepared from commercially available diphenylacetate derivatives, and substituted with 1-propanol to produce diphenylpropoxy acetic acid esters. After the transesterification reaction with 4-hydroxy-N-methylpiperidine to provide a high-purity propiberine hydrochloride to provide a novel production method that is safer than the existing method and low production cost. [Formula 1] |
| priorityDate | 2010-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.