http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100910333-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate | 2006-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100910333-B1 |
| titleOfInvention | Quinazolin Derivatives Having Tyrosine Kinase Inhibitory Activity |
| abstract | A compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof or a solvate of the compound or salt:n n n n n n n n [Wherein R X is a group represented by the following formula (II):n n n n n n n n {In formula, R 1 means a hydrogen atom, an alkyl group which can be substituted, etc., Z means -O-, -N (R 10 )-, etc., R 10 means a hydrogen atom, an alkyl group, etc., R 2 means a hydrogen atom, an alkyl group which may be substituted, and the like, R 18 means a hydrogen atom, an alkyl group which may be substituted, and the like, R 19 means an alkyl group which may be substituted, and W 1 may be substituted. Non-aromatic nitrogen-containing heterocyclic group, and the like, and R 17 means a hydrogen atom, an alkyl group which may be substituted, and the like; R 3 and R 4 independently represent a hydrogen atom, an alkyl group which may be substituted, and the like; X means -O-, -S-, -N (R 12 )-and the like; R 12 means a hydrogen atom, an alkyl group or the like; And A represents a phenyl group which may be substituted, and the like}].n n n The compound can inhibit both EGF receptor tyrosine kinase and HER2 tyrosine kinase. |
| priorityDate | 2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 276.