| abstract |
It is an object of the present invention to provide a neuronal cell death inhibitor which inhibits the constant activation of calcineurin and has little side effects and is effective for various diseases. Inhibitors of homeostasis activation of calcineurin, specifically agents which inhibit the cleavage of calcineurin A subunit (CaNA) by calpine. Examples thereof include peptides having the amino acid sequences of FDGATAAARKEVIRNK (SEQ ID NO: 1) and REESESVLTLKGLTPTG (SEQ ID NO: 2).n n n n Calcineurin, homeostasis, nerve cell death, calpine |