http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100832749-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-01002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 2006-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100832749-B1 |
| titleOfInvention | Method for preparing optically active α-fluoromethyl propargyl alcohol derivative |
| abstract | The present invention relates to a method for preparing an optically active α-fluoromethyl propargyl alcohol derivative, in the presence of a racemic α-fluoro in the presence of a lipase catalyst derived from Candida antarctica or Mucor miehei . The methyl propargyl alcohol derivative is reacted with vinyl alkanoate to perform stereoselective esterification reaction to obtain an optically active compound and ester derivative in the form of (-)-, followed by hydrolysis of the ester derivative in the form of (+)- It is characterized by obtaining the optically active substance of. According to this method of the present invention, the desired optically active α-fluoromethyl propargyl alcohol derivative can be easily obtained from the racemic raw material compound, and the obtained optically active compound has high optical purity of up to 99% ee or more. |
| priorityDate | 2006-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.