http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100766851-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 |
| filingDate | 2001-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100766851-B1 |
| titleOfInvention | Novel α-ketoamide derivatives and methods for their preparation |
| abstract | The present invention provides a novel α-ketoamide derivative of formula (1) having a inhibitory effect on phosphodiesterase IV and tumor necrosis factor (TNFα), and a pharmaceutically acceptable salt and solvate thereof, and a method for preparing the same. It relates to pharmaceutical compositions containing them:n n n [Formula 1]n n n n n n n n Wheren n n R 1 and R 1 ′ are the same as or different from each other and represent H, OH or OR 2 , wherein R 2 represents a (C 1 -C 7 ) alkyl group, (C 3 -C 7 ) cycloalkyl group or Bn,n n n R 3 represents hydrogen,n n n R 4 is , Orn n n R 3 and R 4 together with the nitrogen atom to which they are attached, Can form a heterocyclic ring ofn n n From here,n n n X and Y are the same as or different from each other, and represent a hydrogen atom or a halogen atom,n n n Z represents CH or N,n n n A represents a CH 2 , S, O or NR 5 element, wherein R 5 represents H or a (C 1 -C 7 ) alkyl group,n n n n represents the number of 1-3. |
| priorityDate | 2001-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.