| abstract |
The present invention is a base metal, a thin film of gold or silver coated on the surface of the base metal, a functional sulfur compound adsorbed on the gold or silver thin film, heparin chemically bonded to the functional group of the sulfur compound Or surface modified medical metal materials comprising bioactive substances such as estradiol derivatives and stents, heart valves and catheter fabricated using the same. In addition, the present invention (1) coating a thin film of gold or silver on the surface of the base metal, (2) adsorbing a functional sulfur compound on the gold or silver thin film, and (3) Disclosed is a method of making a surface modified medical metal material, comprising chemically bonding an active substance. |