| abstract |
Novel antibody that recognizes the extracellular domain of human CLCP1 antigen, nucleic acid encoding the antibody, vector retaining the nucleic acid so that it can be expressed, transformed cell having the vector, method for producing the antibody, and using the antibody Cancer diagnosis method and prognosis diagnosis method, cell or tissue immunological measurement method, kit for detecting CLCP1 expression level in cell or tissue, and pharmaceutical composition containing the antibody, CLCP1 is expressed For use in the treatment or prevention of cancer, growth / migration / invasion / metastasis inhibitors of cancer cells expressing CLCP1 and immunostaining, and for use in the treatment or prevention of tumors expressing CLCP1 Provide drugs. Furthermore, the present invention provides a screening method for a candidate substance that inhibits proliferation, invasion, migration, or metastasis of cancer cells, or a candidate substance that has cytotoxic activity on cancer cells. |