| titleOfInvention |
A novel polypeptide ESDN, a method for producing the same, a cDNA encoding the same, a vector comprising the cDNA, a host cell transformed with the vector, an antibody of the ESDN, a pharmaceutical composition containing the ESDN or the antibody, and an ESDN. Screening method, and method for immunochemical assay of ESDN using anti-ESDN antibody |
| abstract |
(57) [Summary] Novel polypeptide ESDN, a method for producing the same, cDNA encoding the ESDN, a vector comprising the cDNA, a host cell transformed with the vector, an ESDN antibody, an ESDN or an antibody Pharmaceutical composition, method for measuring ESDN, reagent for measuring ESDN, and screening method using ESDN. Effect The ESDN protein of the present invention is expressed in coronary artery cells and smooth muscle cells, and is expressed in vascular smooth muscle of balloon-injured arteries and in the media of common carotid artery. It is useful for treating restenosis and arteriosclerosis. |