| abstract |
As a heat shock protein 90 (Hsp90) family protein inhibitor, formula (I) [Wherein n represents an integer of 1 to 5, R 1 represents substituted or unsubstituted lower alkyl, CONR 7 R 8 (wherein R 7 and R 8 are the same or different and represent a hydrogen atom, substituted or unsubstituted lower alkyl, etc.) and the like, R 2 represents substituted or unsubstituted aryl, etc. R 3 and R 5 are the same or different and each represents a hydrogen atom, a substituted or unsubstituted lower alkyl, and the like, R 4 represents a hydrogen atom or the like, R 6 represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like], or a therapeutic agent for cancer having protease inhibitor resistance, or the like, containing a benzoyl compound represented by the formula: provide. |