| abstract |
Disclosed is a compound that can be used for the treatment of diseases involving fatty acid amide hydrolase (FAAH), particularly frequent urination, urinary incontinence, and / or overactive bladder. The present invention was completed by confirming that a urea compound or a salt thereof characterized by having a piperidine ring or a piperazine ring in terms of chemical structure has good FAAH inhibitory activity. Furthermore, since the urea compound of the present invention or a pharmaceutically acceptable salt thereof showed a good effect of increasing the effective bladder dose and improving the frequent urination, frequent urination, urinary incontinence and / or excessive It is useful as a therapeutic agent for active bladder. [Selection figure] None |