| abstract |
Describes 4- (2,2-difluoro-benzo [1,3] dioxol-5-ylmethyl) -piperazine-1-carboxylic acid (4-chloro-pyridin-3-yl) -amide useful as a FAAH modulator To do. 4- (2,2-difluoro-benzo [1,3] dioxol-5-ylmethyl) -piperazine-1-carboxylic acid (4-chloro-pyridin-3-yl) -amide is anxiety, pain, inflammation, Drugs for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (eg, multiple sclerosis) It can be used in compositions and methods. Also disclosed is a method of synthesizing 4- (2,2-difluoro-benzo [1,3] dioxol-5-ylmethyl) -piperazine-1-carboxylic acid (4-chloro-pyridin-3-yl) -amide. . |