| abstract |
Formula (I) [Chemical Formula 1] [wherein Cy represents an aromatic hydrocarbon group which may be substituted or an aromatic heterocyclic group which may be substituted, and R1 may be a hydrogen atom or a substituted group. Represents a good hydrocarbon group, V represents -C (O)-, -S (O)-or -S (O) 2-, and W represents -N (R2)-, -O- or a bond. (R2 represents a hydrogen atom or an optionally substituted hydrocarbon group), X represents an optionally substituted alkylene, and Y represents —C (O) —, —S (O) — or —S ( O) 2−, Z represents a bond, an optionally substituted chain hydrocarbon group or —N═, ring A represents an optionally substituted non-aromatic nitrogen-containing heterocycle, B represents an optionally substituted nitrogen-containing heterocyclic ring, [Chemical Formula 2] each independently represents a single bond or a double bond, and R 1 is bonded to R 2 to be substituted. An aromatic nitrogen-containing heterocycle may be formed, and R2 may be bonded to a substituent of X to form a non-aromatic nitrogen-containing heterocycle which may be substituted. The urea derivative useful as a thrombosis therapeutic agent represented by these, or its salt is provided. |