http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6372672-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1986-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c78d50133246ed8b24f359ce49c9f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4637953de4fc8fd2a509946b9fc404c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c770f8fe49600c6a4da6a0e813be59 |
| publicationDate | 1988-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6372672-A |
| titleOfInvention | 2-fluoro-4-hydroxy-2-cycropentenones and production thereof |
| abstract | NEW MATERIAL:A compound expressed by formula I (R 1 is 1W10C alkyl; R 2 is alkyl or alkenyl; R 3 is H, tri 1W7C hydrocarbon silyl or group capable of forming a acetal bond with O of group; A and B are respectively H and OH or one bonding hand linked with A and B). n EXAMPLE: 2-Fluoro-5-(1-hydroxy-6-methoxycarbonylhexyl)-4-octyl-4-trimethylsilyl oxy-2-cyclopentenone. n USE: Anticancer agent, showing strong action for inhibiting a cancer cell growth to especially leukemia bacterium in low concentration. n PREPARATION: 2-Fluoro-4-hydroxy-2-cyclopentenones expressed by formula II (R 30 is tri 1W7C hydrocarbon silyl or group capable of forming an acetal bond with O of OH) are subjected to aldol condensation reaction with aldehydes expressed by the formula OHC-C-R 10 (R 10 is 1W10C alkyl) and as necessary, followed by deprotection, hydrolysis and salt-forming reaction to provide a compound expressed by formula I. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1704855-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6696498-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9825593-A3 |
| priorityDate | 1986-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.