http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63245694-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f5ef33cec3537b306a172695f828500 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1987-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b975adbaf5d450014f90098223a6a8de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db5a4a7e4a2846a2a09f40f43232ab39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ff4bc3fcf5dd5c3c161df5c5077a53a |
| publicationDate | 1988-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63245694-A |
| titleOfInvention | Production of optically active sulfur-containing carboxylic acid and antipodal ester thereof |
| abstract | PURPOSE: To readily obtain the titled carboxylic acid and antipodal ester thereof useful for synthesizing various physiologically active substances, etc., in good yield, by reacting a specific ester with a microorganism capable of asymmetrically hydrolyzing ester bonds, etc. n CONSTITUTION: A strain, such as the genus Brettanomyces, capable of asymmetrically hydrolyzing ester bonds is cultivated in a desired synthetic culture medium at pH3W11 and 20W50°C to provide microbial cells, which are then treated to provide a cell-free extract. The resultant extract is subsequently suspended in a reaction medium, such as phosphoric acid buffer solution, and 0.01W50wt.% ester expressed by the formula [R 1 is H (ar)alkyl or aryl; R 2 and R 3 are alkyl; n is 1W20] [e.g. butyl (±)-3-mercapto-2-methyl-propionate] is added to carry out reaction at pH2W12 and 20W90°C. The reaction is then continued until either ester of the d- and l-isomers is completely hydrolyzed to afford a reaction solution, which is then separated and purified by extraction, distillation, column chromatography, etc., to recover the aimed optically active sulfur-containing carboxylic acid and antipodal ester thereof. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0289804-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0534958-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9534525-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5070022-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02498-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03097851-A1 |
| priorityDate | 1986-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.