| abstract |
PURPOSE: To produce an optically active carboxylic acid, in high efficiency, by reacting the corresponding ester with a microbial strain capable of asymmetrically hydrolyzing the ester bond. n CONSTITUTION: An optically active carboxylic acid of formula I (R 1 is alkyl, aralkyl or allyl; R 2 is alkyl; n is 1 or 2) is produced by treating the ester of formula II (R 3 is alkyl; R 1 , R 2 and n are same as defined above) with the cultured liquid, microbial cells or treated cells of a microbial strain capable of asymmetrically hydrolyzing an ester bond and belonging to Torulopsis genus, Bacillus genus, Aspergillus genus, etc. n COPYRIGHT: (C)1985,JPO&Japio |