| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 |
| filingDate |
1986-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c81d68dc42e4ab044874a361051ae275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_182762ec51540bb3743ef077313c0853 |
| publicationDate |
1987-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S62240651-A |
| titleOfInvention |
Production of optically active 1-substituted-2-aminopropane |
| abstract |
PURPOSE: To obtain the titled compound useful as a synthetic intermediate for various pharmaceuticals, either by reducing an optically active 3- substituted-2-aminopropanol derivative in the presence of a metal halide or by reacting said compound with a metal halide and reducing the reaction product. n CONSTITUTION: The objective compound of formula III can be produced either by (1) reacting a compound of formula I [R 1 is (substituted) aryl or nitrogen- containing heterocyclic group; OZ is protected OH; -NHY is (protected) amino] or its salt with a reducing agent (e.g. metallic zinc) in the presence of a metal halide (e.g. sodium iodide) at 20W100°C or by (2) reacting the compound of formula I or its salt with a metal halide in a mixed solvent of water and THF, etc., at 120W100°C and reducing the resultant corresponding propyl halide of formula II (X is halogen). n EFFECT: The objective compound can be produced from an easily available raw material in high purity and yield. n COPYRIGHT: (C)1987,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6992205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6794519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6864372-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0194304-A1 |
| priorityDate |
1986-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |