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filingDate 1985-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a488c655b7930322147edbd9e6fc412d
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publicationDate 1986-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S61275216-A
titleOfInvention Anti-inflammatory and analgesic ointment
abstract PURPOSE: To obtain an anti-inflammatory analgesic ointment giving low stimulation to skin and having high absorbability, by compounding indomethacin with a basic amino acid as a dissolution agent, a gelling agent, and carrageenan, xanthan gum, etc., as a thickener at specific ratios. n CONSTITUTION: The objective ointment can be produced by mixing (A) 0.5W1.5wt% indomethacin with (B) a medium composed of 0.5W10wt% basic amino acid, 10W60wt% lower alcohol and 20W60wt% water and (C) a gelling agent or thickener consisting of one or more components selected from carageenan, furcellaran, locust bean gum and xanthan gum, and adding 0.5W10wt% lactic acid ester (preferably containing 12W18C alcohol component) as an absorbent. The skin stimulation and stickiness are decreased compared with an ointment containing glucose as a dissolution agent. It has high spreadability and is producible easily without necessitating the control of pH. It has high absorbability into the skin. n COPYRIGHT: (C)1986,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003507438-A
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priorityDate 1985-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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