http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02196714-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1755eede76ea7e719a3e0d2843cd793 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
filingDate | 1989-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a014b8b5ce3094a1e8495d5c64909f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f55cf93d2a5239d479d0e4d534cfbc56 |
publicationDate | 1990-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H02196714-A |
titleOfInvention | Spreading plaster of percutaneous absorption |
abstract | PURPOSE: To obtain the title spreading plaster having high permeability of drug through skin, releasing each given amount for a long period of time by adding estradiol (ester) and lactic ester to a tacky layer containing a copolymer of a specific composition capable of dissolving the drug in high concentration. n CONSTITUTION: 6-25wt.%, preferably 8-20wt.% estradiol and/or ester thereof and 1-100 pts.wt. based on 100 pts. wt. tacky base of a higher fatty acid ester obtained from lactic acid and 1-20C alcohol and/or a higher fatty acid ester prepared from 10-18C fatty acid and 1-20C alcohol as a percutaneous absorption promoter are added to a tacky agent base layer comprising a copolymer containing 45-80mol%, preferably 55-70mol% 2-ethylhexyl acrylate and 20-55mol%, preferably 30-45mol% N-vinyl-2-pyrrolidone as a tacky base and the tacky agent layer is laid on a drug-impermeable flexible substrate. The tacky agent layer has no skin irritation and can avoid skin disorder such as flare. n COPYRIGHT: (C)1990,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6797280-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9802147-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1222923-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0395119-A |
priorityDate | 1989-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.