| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-401
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate |
1985-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8dc3cdd21a4011a9929f9c5fabe3cdc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4392c94af6f207ab162ceafe316f734
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_804473f4bdc730c623b8d7fe8106fdf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08f7e05b43b20aea4d8bdacd973efa2a |
| publicationDate |
1986-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S61238775-A |
| titleOfInvention |
Peptidase-inhibiting compound, production and use thereof |
| abstract |
NEW MATERIAL:The compound of formula I (R is -CH 3 or group of formula II or III). n EXAMPLE: N-(4-phenyl-n-butanoyl)-alanyl-Pro-ol (Pro-ol is group of formula IV). n USE: Medical drug. A prolylendopeptidase-inhibiting agent and antiamnestic agent. n PREPARATION: The compound of formula I can be produced by dissolving the ester of formula V (R' is CH 3 of lower alkyl) and NaBH 4 in tert-butyl alcohol, reacting with methanol under refluxing to produce the alcohol of formula VI and oxidizing the alcohol with sulfur trioxide-pyridine complex in dimethyl sulfoxide. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01156957-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008521853-A |
| priorityDate |
1985-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |