http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61227593-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 |
| filingDate | 1985-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c39380a6748922a89acf3673667f56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07acd45dd1c4cc155e030a761f04a8b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a5413caefad16a0063267bf7cc51779 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_325ed28a54bee72b0ec2f41089b93d9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b286a0a0f7c941fd0e588822fe5b97ac |
| publicationDate | 1986-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61227593-A |
| titleOfInvention | Preparation of alpha-l-aspartyl-l-phenylalanine methyl ester or its hydrochloride |
| abstract | PURPOSE: Methyl benzyldioxopiperazinylacetate is brought into contact with hydrochloric acid is followed by allowing the product to crystallize out of the reaction system in the form of its hydrochloride to enable high-efficiency and high-yield production of the titled compound. n CONSTITUTION: Methyl 5-benzyl-3,6-dioxo-2-piperazinylacetate, as a starting material is brought into contact with hydrochloric acid, when necessary, in the presence of methanol, preferably at 10W60°C to crystallize out the objective compound in the form of its hydrochloride. Further, when needed, the hydrochloride is neutralized with an alkali such as sodium hydroxide. The hydrochloric acid is used in the form of an aqueous solution and its concentration is 5W30wt%. The amount of hydrochloric acid employed is preferably 1.1W10mol per mol of the starting substance. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63145298-A |
| priorityDate | 1985-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.