| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0613 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 |
| filingDate |
1984-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e854efe7ce08bb0dde2acf5b7fe8be1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e13cf8c7f2403309c2b626d353adae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a39fe241207af2ed6367b6266c3a6b1a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4905bb07a86d4fb099d82beb8a0380d7 |
| publicationDate |
1985-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S60174799-A |
| titleOfInvention |
Preparation of alpha-l-aspartyl-l-phenylalaninemethyl ester |
| abstract |
PURPOSE: To obtain the titled substance useful as a sweetener with low calorie industrially advantageously, by hydrolyzing partially benzyl-carboxymethyl- diketopiperazine with a strong acid in a mixed solvent consisting of methanol and water. n CONSTITUTION: 3-Benzyl-6-carboxymethyl-2,5-diketopiperazine(α-AP.DKP for short) is partially hydrolyzed with a strong acid preferably hydrohalogenic acid such as hydrochloric acid, etc.) in a mixed solvent of methanol and water (in a molar ratio of preferably 0.01W1.0) at 20W80°C, to give the desired compound. The concentration of the strong acid is preferably ≤10M/l. n COPYRIGHT: (C)1985,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4801732-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61227593-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4918216-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4962222-A |
| priorityDate |
1984-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |