http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61204171-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692dc75829481c48c017b52f352e2bad |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1985-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfea4f032652a245e3c346be6846eb2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1fcde0422ce6e67f783060426bb338a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d924f2c203ae14776ca7d73b2cb3b647 |
| publicationDate | 1986-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61204171-A |
| titleOfInvention | 5-fluorouracil derivative and medicinal drug preparation containing same |
| abstract | NEW MATERIAL:The 5-fluorouracil derivative of formula (R is acyl derived from triene higher fatty acid or pentaene higher fatty acid). n EXAMPLE: 1-(α-Linoleylaminomethylcarbamoyl)-5-fluorouracil. n USE: A carcinostatic agent and platelet coagulation inhibitor. n PREPARATION: The objective compound of formula is produced by reacting 5-fluorouracil (5-FU) with the compound of formula R-NHCH 2 CO 2 H in a solvent such as dimethylformamide, dioxane, etc., in the presence of diphenylphos phorylazide. The compound exhibits an antitumor activity (carcinostatic activity) comparable to or higher than 5-FU, and has lower toxicity than 5-FU. It has strong platelet coagulation inhibiting activity which cannot be found in 5-FU. It is administered in a dose of preferably about 1W3g daily for adults. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46608-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46605-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486534-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9238077-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9278136-B2 |
| priorityDate | 1985-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.