http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6115698-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a65b677bbedbe7bf090dd556a7cc43 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 |
| filingDate | 1984-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af073dac900f7c4c627aa27cc1b3c5e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63655b6c8c008dd56cadbac898d44627 |
| publicationDate | 1986-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6115698-A |
| titleOfInvention | Preparation of hyaluronic acid |
| abstract | PURPOSE: In the production of hyaluronic acid with a bacterium, to obtain hyaluronic acid having a small amount of protein admixed, by cultivating a bacterium capable of producing hyaluronic acid, bringing the prepared mold into contact with a saccharide. n CONSTITUTION: A bacterium such as Streptococcus pyogenes, Streptococcus equi, etc., capable of producing hyaluronic acid, is cultivated in a common culture solution. The prepared mold is washed with water or a sodium chloride injection, or treated with a crosslinking agent such as glutaraldehyde, etc. and/or an organic solvent such as benzene, toluene, etc., and suspended in a buffer solution at 6W8.5pH. A saccharide such as glucose, fructose, sucrose, etc. is added to the suspension with aeration and stirring, the saccharide is in contact with the mold for a given time, and prepared hyaluronic acid is extracted from the reacton solution by a well-known method. Hyaluronic acid is important as an intercellular substance to fill up gaps between cells, and since it has water retention it is useful as a remedy for wound, eyewash, remedy for arthritis, etc. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0630604-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6328398-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014091980-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2014091980-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0443637-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1085728-C |
| priorityDate | 1984-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.