http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6048963-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1983-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25440c1c5dd4b2cc880a922187f5f52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_520b9cd7b131ee4f1cb8e81827df580c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f67982bde3d5f809f99a870890a3dc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6576e2785f80ae0855620bb32a298632 |
| publicationDate | 1985-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6048963-A |
| titleOfInvention | 26-halogenated vitamin d3 derivative, its preparation and drug comprising it as active ingredient |
| abstract | NEW MATERIAL:A compound shown by the formula I (X is halogen; A is hydroxymethylene, or carbonyl; R is H, or hydroxyl group). n EXAMPLE: 26-Fluoro-24(R)-hydroxyvitamin D 3 . n USE: Useful as a remedy or preventive for bone lesion such as osteoporosis, osteomalacia, etc. Also useful as antitumor agent for differentaiting and introducing human myelogenous leukemia call into normal cell. n PREPARATION: A 26-halogenated cholest-diene derivative shown by the formula II(R' is H, hydroxyl group, or hydroxyl-protecting group; R" is H, or protecting group) is irradiated with ultraviolet rays, subjected to thermal isomerization, and, if necessary, deprotected to give a compound shown by the formula III. The ultraviolet rays have about 200W360nm wavelength range, especially 260W310nm wavelength range. the irradiation is carried out in an inert organic solvent such as hexane, heptane, etc. n COPYRIGHT: (C)1985,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6421-A |
| priorityDate | 1983-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.