http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5978696-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1982-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6769f8defd4fc938e1522235776f29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c006a95a31a2cc3e42cc320eacfd228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e67ed96872fde8ce70877f404f529d4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8043c3660f369a10a36415466c0a9d84 |
| publicationDate | 1984-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5978696-A |
| titleOfInvention | Preparation of optically active oxazolidinone derivative |
| abstract | PURPOSE: To collect unreacted oxazolidinone and to use it for synthesizing β- blocking agent, by treating a racemic modification of oxazolidinone with an enzyme having a stereoselective esterase activity derived from an animal organ. n CONSTITUTION: A racemic modification of 3-alkyl-substituted-5-acyloxymethyloxazolidin-2-one shown by the formula I (X is lower alkyl group; Y is substituted or unsubstituted alkyl, etc.) is treated with a crude enzyme having a stereoselective esterase activity, capable of hydrolyzing the compound shown by the formula I and forming an optically active (-)-3-alkyl-substituted-5-hydroxymethyloxazolidin-2-one shown by the formula II, derived from an animal organ, such as liver, etc. The compound shown by the formula II, an organic acid, and an optically active (+)-3-alkyl-substituted-5-acyloxymethyloxazolidin-2-one shown by the formula III are separated by chromatography, to give a compound shown by the formula III. n COPYRIGHT: (C)1984,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0353918-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60241893-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0534957-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6495752-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01309696-A |
| priorityDate | 1982-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.