http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S59134779-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6918131ce5bf2cf19b25c88e02b92fc6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-095 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate | 1983-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c389e621b8e14a3115470f4a3440310f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c01ab3127570ec67c94ebf692bcc81b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa5a22a081ceecc1888ea88e440a4fec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fef0f17afe1d22306620d547ab9e0999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6082f8ff87a36455e618526816e066a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de54166e1a67ab752535d1ef494fca31 |
publicationDate | 1984-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S59134779-A |
titleOfInvention | Preparation of azetidinone derivative |
abstract | PURPOSE: To prepare an azetidinone derivative useful as an important intermediate of cephalosporin antibiotic substance, in high purity, economically, by reacting a thiazolineazetidinone derivative with sulfonyl bromide in a hydrated organic solvent in the presence of an acid. n CONSTITUTION: The objective compound of formula III can be prepared by reacting the compound of formula I (R 1 is aryl, phenylmethyl, phenoxymethyl, etc.; R 2 is H or carboxyl-protecting group) with the compound of formula II (Ar is phenyl which may have substituent group) in the presence of an acid (e.g. 1W 20% aqueous solution of hydrochloric acid) in a hydrated organic solvent (e.g. methanol) at 0W20°C for 10minW2hr. The molar ratio of the compound of formula I to the compound of formula II is 1:1.0W1.2, and that of the acid to the compound of formula I is 1.0W1.5:1. n COPYRIGHT: (C)1984,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7507812-B2 |
priorityDate | 1983-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.