| abstract |
PURPOSE: Tetrahydrochloride of antibiotics polymyxin S 1 : colorless powder, m.p. 202-213°C (decomp.), the title antibiotics is identified as C 53 H 91 N 15 .4HCl.H 2 O as elementary analysis, optical rotations [α] 2 D 3 O-54.3+-1.7°(C=0.541 in water), IR spectrum 3140cm -1 , 3050cm -1 3050cm -1 , etc., paper chromatography and thin-layer chromatography Rf=ca. 0.35, the composition of amino acids (mole number) is L-threonine (3), D-serine (1), D-phenylalanine (1) and L-2,4-diaminobutyric acid, fatty acid composition is anti-isononanoic acid, etc n COPYRIGHT: (C)1978,JPO&Japio |