abstract |
(57) [Summary]nA composition for delivering a polynucleotide to mucosal cells, nerve cells, or other cells, comprising a GM1-binding protein and a polynucleotide associated with the binding protein, and administering the composition to an animal; and A method of modulating immunity comprising expressing a polynucleotide to cause the animal to elicit an immune response against the product of the polynucleotide; and administering to the animal a GM1-binding protein and a functional polynucleotide, A method of gene therapy, comprising expressing a polynucleotide and the function of the polynucleotide conferring a therapeutic effect on an animal. |