abstract |
(57) [Problem] To provide a method for producing an aminonitrile derivative in a short step and simply. SOLUTION: General formula (I) And an aldehyde represented by the general formula (II): And a primary amine represented by the general formula (III): Is reacted with a silyl cyanide represented by the formula (IV) in the presence of a ytterbium triflate catalyst: (Wherein R 1 and R 2 represent an alkyl group, a cycloalkyl group, etc.). |