abstract |
PROBLEM TO BE SOLVED: To provide a production method for obtaining an aldehyde derivative from a phenol derivative in a high yield and in a simple manner, and further using the aldehyde derivative to obtain a 2- (4-alkoxy-3-cyanophenyl) thiazole derivative. SOLUTION: The following formula (I) [Wherein, R 1 and R 2 are the same or different and each represent a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms. Wherein the phenol derivative represented by the formula (II) is reacted in the presence of hexamethylenetetramine and polyphosphoric acid. [Where R 1 and R 2 are the same as defined in formula (I). And a method for producing an aromatic aldehyde derivative represented by the formula: A method for producing a (cyanophenyl) thiazole derivative. |