abstract |
(57) Abstract: To provide a composition useful as a bioadhesive or a surgical adhesive. A composition comprising fibrillar collagen, a fiber degrading agent, and a polyfunctionally activated hydrophilic synthetic polymer, wherein the fiber degrading agent removes the collagen at pH 7 Present in an amount sufficient to be substantially non-fibrous, the collagen and the hydrophilic synthetic polymer covalently bond to form a collagen-synthetic polymer conjugate. |