| abstract |
The biomedical adhesive according to the present invention provides a reactive surface that adheres or cross-links to tissue and may be used, for example, as a ready-to-use cornea onlay in ophthalmic surgery. The present invention provides a method for bonding a bulk material to a corresponding nucleophilic or electrophilic surface comprising the following steps: for a multifunctionally activated bulk material The compound is attached to the bulk material, and then the functional group of the compound is contacted with the surface under conditions where a covalent bond is formed between the bulk material and the functional group. |