abstract |
(57) [Summary] An inorganic oxide having an infinitely uniform particle size distribution is prepared by bringing the inorganic salt aqueous solution and the inorganic base aqueous solution into contact with each other through the porous membrane (14). Here, the membrane has a large number of pores, thereby precipitating infinitely uniformly monodisperse-sized inorganic oxides on one surface of the membrane and corresponding bases on the second surface of the membrane. To precipitate the salt (Fig. 1). The particles thus prepared can be coated with an organometallic polymer having an organofunctional group capable of binding various organic or biomolecules. The particles thus bound can be purified by in vitro and in vivo systems or immunoassays involving separation steps, other biological assays, biochemical or enzymatic anti-resorption affinity chromatography, cell search and Used for direct transfer of binding molecules to specific sites, including diagnostics and therapy. In yet another example, a liposome composition consisting of an inorganic core of infinitely uniform particle size coated with an amphipathic organic compound and further coated with a second amphipathic vesicle-forming lipid is also described (FIG. 2). ). Also disclosed are novel phenyl lipid compounds that can be used as vesicle-forming lipids (Figure 3). If the magnetic particles are particles having a modified electromagnetic wave absorbing surface (FIG. 4), such particles are capable of producing liposome compositions that provide a method for treating cancer as well as infectious diseases. |