abstract |
(57) [Summary] [Object] To provide a protein or peptide containing at least one epitope of the cedar pollen allergen Cryj II, particularly a T cell epitope, which is useful for diagnosis, prevention and treatment of cedar pollinosis. [Constitution] cD coding for cedar pollen allergen Cry j II The NA was cloned to reveal the entire amino acid sequence of Cry j II. Furthermore, by synthesizing overlapping peptides over the entire length of the amino acid sequence, Cry derived from cedar pollinosis patients was synthesized. The j II T cell line was used to identify overlapping peptides containing T cell epitopes. |