abstract |
(57) [Summary] [Structure] trans-N- (1H-pyrazolo [3,4- b] Pyridin-4-yl) -4-guanidinomethylcyclohexanecarboxamide / 1 methanesulfonate / 1 Hydrate. [Effect] The monomethanesulfonate monohydrate of the present invention is a salt which exhibits high solubility, does not exhibit hygroscopicity, and has high stability in an aqueous solution, and in particular, an inhalant (solution, powder) It is a useful salt that can be used in any formulation such as, injections, and eye drops. |