| abstract |
(57) [Summary] [Structure] Belonging to the genus Humicola, general formula (1) (In the formula, when R 1 is a hydrogen atom, R 2 represents a methyl or isopropyl group, and when R 1 is a methyl group, R 2 represents a methyl group) The ability to produce a FO-2942 substance Culturing a microorganism having a The O-2942 material was allowed to accumulate and the FO- 2942 substances are collected. [Effect] Since the FO-2942 substance exhibits diacylglycerol acyltransferase inhibitory activity, it is useful for the prevention and treatment of diseases caused by triacylglycerol accumulation in humans. |