| abstract |
(57) [Summary] (Modified) [Structure] A morpholine and thiomorpholine derivative having the general formula (I) or a salt thereof. Wherein, R 1, R 2, R 3, R 4 and R 5 are a hydrogen atom, a halogen atom, C 1 -C 5 alkyl group, C 1 -C 5 Alkoxy group, OH, CF 3 ; R 6 is hydrogen atom, C 1 The -C 5 alkyl group; A is O, and S; B is a bond, O, The S; X is O, a CH; Y is NH, O, and S; Z is a hydrogen atom, a group - (CH 2) a n -CO 2 R 7; R 7 is a hydrogen atom, C 1 -C 5 alkyl A group; n is an integer of 1 to 5] [Effect] The compound is useful as a preventive and / or therapeutic drug for hyperlipidemia, hyperglycemia and obesity, as well as hypertension and osteoporosis. |