abstract |
(57) [Summary] [Structure] α-anomer-rich 2-deoxy-fluoro- Stereoselective Preparation of 2'-Deoxy-2 ', 2'-difluoronucleosides Enriched in β Anomers by Reacting 1-Halogen Carbohydrates with At least Equimolar Salts of Nucleobases in an Inert Solvent Anionic glycosylation methods are provided. [Effect] By the method of the present invention, a β-nucleoside compound can be produced in high yield. |