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filingDate 2009-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5da714b3461af95b76ed9dd81a88417c
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publicationDate 2010-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2010070560-A
titleOfInvention Method for the synthesis of 2-chloro-9- (2-deoxy-2-fluoro-β-D-arabinofuranosyl) -9H-purin-6-amine
abstract PROBLEM TO BE SOLVED: To provide a relatively high yield synthesis method of 2-chloro-9- (2-deoxy-2-fluoro-β-D-arabinofuranosyl) -9H-purin-6-amine. A method for synthesizing 2-chloro-9- (2-deoxy-2-fluoro-β-D-arabinofuranosyl) -9H-purin-6-amine, comprising: a) An anionic form of 2-chloro-6-substituted purine (wherein the substituent at the 6-position of 2-chloro-6-substituted purine is selected from the group consisting of an amino group and a protected amino group) Reacting the protected and activated 2-deoxy-2-fluoro-D-arabinofuranose; b) A synthesis method characterized by reacting with ammonia to obtain 2-chloro-9- (2-deoxy-2-fluoro-β-D-arabinofuranosyl) -9H-purin-6-amine. [Selection figure] None
priorityDate 2000-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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