| abstract |
(57) [Summary] [Structure] General formula [Chemical formula 1] (R 1 is a hydrogen atom, a nitro group, a group represented by —N (R 4 ) R 5 , R 2 and R 3 are hydrogen atoms or a lower alkyl group, and R 4 and R 5 are a hydrogen atom and a lower alkyl group. , R 4 And R 5 may be integrated to form a cyclic amino group) A 3,5-dihydroxyheptanoic acid derivative represented by: [Effect] Since these 3,5-dihydroxyheptanoic acid derivatives have an HMG-CoA reductase inhibitory action, a cholesterol lowering action and a lipid peroxide production inhibiting action, they can be used for the treatment of arteriosclerosis. |